ORCHARD PARK, N.Y. — The Buffalo Bills 2022 schedule has been released, and the team continues its trend of playing in the national spotlight.

Five primetime games highlight the slate. The Bills also play on Thanksgiving for the third time in four seasons.

Preseason

  • Week 1: Saturday, Aug. 13 vs. Indianapolis Colts, 4 p.m.
  • Week 2: Saturday, Aug. 13 vs. Denver Broncos, 1 p.m.
  • Week 3: Date TBD, at Carolina Panthers, time TBD

Regular season

  • Week 1: Thursday, Sept. 8 at Los Angeles Rams, 8:20 p.m.
  • Week 2: Monday, Sept. 19 vs. Tennessee Titans, 7:15 p.m.
  • Week 3: Sunday, Sept. 25 at Miami Dolphins, 1 p.m.
  • Week 4: Sunday, Oct. 2 at Baltimore Ravens, 1 p.m.
  • Week 5: Sunday, Oct. 9 vs. Pittsburgh Steelers, 1 p.m.
  • Week 6: Sunday, Oct. 16 at Kansas City Chiefs, 4:25 p.m.
  • Week 7: BYE WEEK
  • Week 8: Sunday, Oct. 30 vs. Green Bay Packers, 8:20 p.m.
  • Week 9: Sunday, Nov. 6 at New York Jets, 1 p.m.
  • Week 10: Sunday, Nov. 13 vs. Minnesota Vikings, 1 p.m.
  • Week 11: Sunday, Nov. 20 vs. Cleveland Browns, 1 p.m.
  • Week 12: Thursday, Nov. 24 (Thanksgiving) at Detroit Lions, 12:30 p.m.
  • Week 13: Thursday, Dec. 1 at New England Patriots, 8:15 p.m.
  • Week 14: Sunday, Dec. 11 vs. New York Jets, 1 p.m.
  • Week 15: Saturday or Sunday, Dec. 17 or 18 vs. Miami Dolphins, time TBD
  • Week 16: Saturday, Dec. 24 at Chicago Bears, 1 p.m.
  • Week 17: Monday, Jan. 2 at Cincinnati Bengals, 8:30 p.m.
  • Week 18: Saturday or Sunday, Jan. 7 or 8 vs. New England Patriots, time TBD