SAN ANTONIO -- The Spurs are just over a week out from the start of the regular season, but they're already down two key players. 

On Sunday night, during the Spurs pre-season loss to the Houston Rockets, Dejounte Murrary sustained a knee injury and limped off the court. On Monday morning, the team confirmed the third-year point guard tore his ACL.

MORE | Spurs' Murray to undergo MRI after Injuring Right Knee 

Murray was previously expected to start this season, taking over after Tony Parker departed over the summer for the Charlotte Hornets after 17 seasons in San Antonio. 

The team did not announce a timeline for Murray's return, but this type of injury can be potentially season-ending. 

"I feel bad for the team because they were all so high on Dejounte, but mostly for him, because he's worked hard, he's improved. But, you know, he's had other injuries earlier that kept him out, and he just recovered and was really getting into the flow of things, and for this to happen was really a setback," said Gregg Popovich, Spurs head coach.

Prior to Murray's injury, on Friday's pre-season win over the Detroit Pistons, rookie Lonnie Walker IV also suffered a knee injury.

On Saturday, the team announced that he had an MRI scan showing a meniscus tear in his right knee, with surgery planned for Monday. He is estimated to be out for six to eight weeks.