Kennan Robertson scored 18 points as Irondequoit held off Churchville, 64-62 to advance in Class A1 boys.
Luke Melidona hit a pair of free throws with 1:07 to play as the Eagles held off the Saints, who rallied from 14 points down to tie the game.
Top-seeded Irondequoit faces number four Pittsford Mendon, the Vikings are the defending Class A1 Champions.
In the other semifinal at Webster Schroeder on Wednesday, Eastridge will play Leadership. The Lancers scoring a 63-56 win over Greece Athena in the quarters while the Lions edged Spencerport 67-62.