NEWTON, Mass. - Closures on the Mass Pike this weekend are expected to lead to major delays. 

The Massachusetts Department of Transportation said all but one lane in each direction will be closed near Interstate 95 in the Newton/Weston area from nine o'clock Friday night until Monday morning. 

It's part of their bridge replacement project.

The bridge crosses over MBTA commuter rail tracks, which will also be shut down during the construction.

Highway Administrator Jonathan Gulliver has advice for people who may be traveling from central and western Massachusetts. 

“You have a couple of different choices” said Gulliver. “You could go north and jump on to Route 2 to get in. Frankly, that's the way I would go because it ensures that you're going to be missing most of it. But Route 9 is certainly an option. But I think the number one thing I would tell people though, is these mapping apps are really great tools. They have built in all the traffic analysis. They're going to route you on the best possible way to go. And there's going to be times where going right through the project site might be the most efficient way. So, regardless of what tools you're using, though, we're really telling everybody, plan ahead. You have to be prepared to leave early."

Gulliver said train travel will also be impacted and shuttle buses will be offered. 

MassDOT said delays could reach up to three hours.

The same delays are expected again in three weeks when MassDOT replaces the other side of the bridge.