Rondell Watson scored 31 points including the 1,000th of his career as Leadership held off McQuaid, 81-76.
Kennyh Hardeman scored 20 points as Leadership led by double digits in the second half. The Knights (6-2) rallied late behind 26 points from Jermaine Taggert, but suffer their first loss to a Section V team this season.
The victory snapped a three-game skid by the Lions. Watson hit a three-pointer early in the third quarter to reach the 1,000 point plateau.