The U.S. has hit a new record for the number of coronavirus cases reported in a single day, with more than 126,000 new cases reported Thursday. The U.S. also reported another 1,186 deaths, according to the COVID Tracking Project database.

The news comes one day after the U.S. broke the record with over 116,200 new cases on Thursday, as well as 1,124 deaths.

There are currently 55,000 people hospitalized with COVID-19.

In the last week, coronavirus infections have increased in every U.S. state. Some of the current hotspots include the Midwest, with states like Illinois, Iowa, Minnesota, Ohio and Wisconsin increasing cases by 10% or more in the last seven days. 

At least 235,000 Americans have died from the virus, according to Johns Hopkins University. More than 53,000 are hospitalized with COVID-19, another metric that’s been increasing in recent weeks. Hospitalizations reached a low in September when they dipped below 30,000.

A key model from the University of Washington predicts nearly 400,000 total U.S. deaths by Feb. 1, but it also estimates more than 50,000 lives could be saved with universal mask use.

Public health experts fear potentially dire consequences, at least in the short term.

Trump’s current term doesn’t end until Jan. 20. In the 86 days until then, 100,000 more Americans will likely die from the virus if the nation doesn’t shift course, said Dr. Robert Murphy, executive director of the Institute for Global Health at Northwestern University’s Feinberg School of Medicine, echoing estimates from other public health experts.

“Where we are is in an extremely dire place as a country. Every metric that we have is trending in the wrong direction. This is a virus that will continue to escalate at an accelerated speed and that is not going to stop on its own,” said Dr. Leana Wen, a public health expert at George Washington University.

Dr. Susan Bailey, president of the American Medical Association, said there are things Americans can do now to help change the trajectory.

“Regardless of the outcome of the election, everyone in America needs to buckle down,″ Bailey said.

“A lot of us have gotten kind of relaxed about physically distancing, not washing our hands quite as often as we used to, maybe not wearing our masks quite as faithfully. We all need to realize that things are escalating and we’ve got to be more careful than ever,” she said.

Polls showed the public health crisis and the economy were top concerns for many Americans.

They are competing issues that Trump and Biden view through drastically different lenses.

Trump has ignored the advice of his top health advisors, who have issued increasingly urgent warnings in recent days about the need for preventive measures, instead holding rallies where face coverings were rare and falsely suggesting that the pandemic is waning.

By contrast, Biden has rarely been seen in public without a mask and made public health a key issue. Whether his voice will carry much influence if Trump is declared the winner is uncertain.

“President Trump has already made clear what his strategy is for COVID-19, which is to pretend that there is not a contagious virus all around us,” Wen said. Trump has been touting treatments and vaccines, which won’t be widely available to all Americans until at least mid-2021, she noted.

“There’s a lot of suffering that is going to happen before then, which could have been prevented,” Wen said.

Federal health officials have said they believe a vaccine could get emergency use authorization before the end of the year. The first limited supplies of doses would then be immediately distributed to the most vulnerable populations, which is likely to include frontline health care workers. Doses would then gradually become more widely available.

The timeline hinges on having a vaccine that’s shown to be safe and effective, which experts note is not yet a certainty. “The vaccine has to move at the speed of science,” said Dr. Joshua Sharfstein, vice dean for public health practice at Johns Hopkins University and former Maryland state health department chief.

On the treatment front, the makers of two experimental antibody drugs have asked the Food and Drug Administration to allow emergency use of them for people with mild to moderate COVID-19, and Trump, who received one when he was sickened last month, has said he wanted them available right away.

So far, the FDA has granted full approval to only one drug — the antiviral remdesivir — for hospitalized patients. Dexamethasone or similar steroids are recommended for certain severely ill patients under federal treatment guidelines.

The government continues to sponsor many studies testing other treatments alone and in combination with remdesivir.

But the development of treatments could be affected if Trump makes good on threats to fire Dr. Anthony Fauci, the government’s top infectious disease doctor, or other top health officials Trump has clashed with.

Most Americans support mandating mask-wearing in public and think preventing the virus from spreading is a higher priority than protecting the economy, according to AP VoteCast, a nationwide survey of over 133,000 voters and nonvoters conducted for The Associated Press by NORC at the University of Chicago.

While several European countries have imposed or proposed new lockdowns and other restrictions to control surging cases, Trump has resisted those approaches and has focused on rebuilding the economy.

Absent a national pandemic strategy, curbing virus spread in the U.S. will depend on more Americans taking necessary precautions and the upcoming holiday season will make that a challenge, said Dr. Cedric Dark, an emergency physician in Houston.

“It’s going to be Thanksgiving, winter break for college students, Christmas time and Hannukah,” but families may have to resist close get-togethers this year, he said. Outbreaks on college campuses mean many students may be bringing the virus home and spreading it to parents and grandparents, he said.

Dark, who hasn’t seen his parents in over a year, has had to adjust his own holiday plans. This year, Thanksgiving will be in his parents’ garage, with the door up, chairs at least 6 feet apart, and a space heater if needed.

“We can at least see each other, from a distance,” Dark said.

The Associated Press contributed to this report.