The Buffalo Bills on Wednesday released their schedule for the 2025 NFL season.

This is the final year the Bills will play at Highmark Stadium, their home since 1973, before moving across the street to New Highmark Stadium to begin the 2026 season.

The team will have a total of five primetime games this season.

The Bills will kick off the season at home against two-time MVP quarterback Lamar Jackson and the Baltimore Ravens, and will end the regular season at home against the New York Jets — the first opponent the Bills ever played against in what was then known as Rich Stadium.

The full regular season schedule:

  • Week 1: Sunday, Sept. 7, vs. Baltimore Ravens at 8:20 p.m.
  • Week 2: Sunday, Sept. 14, at New York Jets at 1 p.m.
  • Week 3: Thursday, Sept. 18, vs. Miami Dolphins at 8:15 p.m.
  • Week 4: Sunday, Sept. 28, vs. New Orleans Saints at 1 p.m.
  • Week 5: Sunday, Oct. 5, vs. New England Patriots at 8:20 p.m.
  • Week 6: Monday, Oct. 13, at Atlanta Falcons at 7:15 p.m.
  • Week 7 — BYE
  • Week 8: Sunday, Oct. 26, at Carolina Panthers at 1 p.m.
  • Week 9: Sunday, Nov. 2, vs. Kansas City Chiefs at 4:25 p.m.
  • Week 10: Sunday, Nov. 9, at Miami Dolphins at 1 p.m.
  • Week 11: Sunday, Nov. 16, vs. Tampa Bay Buccaneers at 1 p.m.
  • Week 12: Thursday, Nov. 20, at Houston Texans at 8:15 p.m.
  • Week 13: Sunday, Nov. 30, at Pittsburgh Steelers at 4:25 p.m.
  • Week 14: Sunday, Dec. 7, vs. Cincinnati Bengals at 4:25 p.m.
  • Week 15: Sunday, Dec. 14, at New England Patriots at 1 p.m.
  • Week 16: Sunday, Dec. 21, at Cleveland Browns at 1 p.m.
  • Week 17: Sunday, Dec. 28, vs. Philadelphia Eagles at 4:25 p.m.
  • Week 18: TBD vs. New York Jets TBD